Drug interactions are reported among people who take Memantine and Modafinil. I kept getting sucked into reading random things like text messages. Compulsivity is a cross-disorder trait underlying phenotypically distinct psychiatric disorders that emerge in childhood or adolescence. With Memantine, tolerance goes down for every drug, it's incredible, and I can't believe this drug it's not more discussed in BL. Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. Modafinil has shown some success in treating ADHD (mixed anecdotal reports, however), and Memantine is there not so much for the tolerance (may not work for Modafinil tolerance anyway) as its agonism of the D2 receptor and anti-ADHD effects of its own. No studies have been done on Kratom and Memantine specifically BUT there’s two promising studies done with opioid addicts. Then I went to modafinil. All rights reserved. Memantine and Modafinil drug interactions by gender *: Memantine and Modafinil drug interactions by age *: Personalize this study to your gender and age (0-99+), and then find any serious effects. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Modafinil also has a mild appetite suppressing effect , which may be good for quitters who want to avoid getting a bit plump. Wonderful synergy between Modafinil/adrafinil and Memantine! 5 comments. On eHealthMe, our answer is simple: run your own phase IV clinical trial. Memantine. share. For about a month. Modafinil side effects. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. It's strange, and I haven't decided if it's wholesome or sinister, although my experiences lead me to suspect the latter. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.. Modafinil can cause skin reactions that may be severe enough to need treatment in a hospital. Page 1 of 2 - How to Potentiate Modafinil - posted in Brain Health: I have a very limited amount of modafinil available and want to pro-long effects (final year medstudent here). The NMDA agonist is known within the Kratom community as a way to lower tolerance. 2014 . Use memantine regularly to get the most benefit. I tried to do low doses of each because that seemed like the way to do it, but I probably overshot the memantine. Modafinil is better by itself, and at least 100mg for long stretches of programming/writing. generic drugs) are not considered. But adrafinil is no more taxing on the liver than alcohol. Get your prescription refilled before you run out of medicine completely. Another idea I had was Modafinil + Wellbutrin (both in highly reduced doses). It is often used in narcolepsy. Use Matcha tea. Receive 10% off your first order! On Sep, 18, 2020 Memantine 20mg x 30ml $ 29.95 Add to cart. The memantine dosage will differ based on the use case. I was interested in trying this combo for long lasting energy and focus for writing, since both modafinil and memantine linger for a long time. hide. Common interactions include chronic obstructive pulmonary disease among females and constipation among males. It is less preferred than acetylcholinesterase inhibitors such as donepezil. save. Start now, it's free and anonymous. A sub for discussing all uses of Memantine, from therapeutic to recreational. The clouds looked beautiful through the window. On Modafinil for about 3 months now. One interesting memantine side effect includes higher libido. Start now. Despite the effectiveness of serotonergic compounds in the treatment of obsessive-compulsive disorder, treatment-resistant symptoms remaining in 40 to 60 % of patients present a pressing clinical problem. Related publications that referenced our studies, "Cataplexy as a side effect of modafinil in a patient without narcolepsy". I calmed down and tried to write some more, but overall I felt like the memantine was outweighing the modafinil too much and making it hard to hold much in my head. hide. This is probably the last time I'll use memantine for productivity, although it could be interesting to use for painting or sculpting sometime as those are better suited to the headspace. I smoked weed, which helped me write some more at first, but then I took a big bong rip and my heart started racing for awhile in a really uncomfortable way, something I've experienced while combining weed with modafinil and memantine separately. 17. Caffeine and piracetam seemed to have done the trick in the past but not too sure now. The phase IV trial will monitor drug safety outcomes that are personalized to your gender and age (0-99+). Keep the liquid medicine bottle tightly closed with the cap provided. Dosage & Usage : Many people find Modafinil VERY stimulating, I would not recommend that people take the 400 milligrams used in the Yale study. For this reason, we will investigate the p… eHealthMe is studying from 5,215 Memantine users now. Two of the most commonly used drugs for the treatment of ADHD in children and adolescents are Adderall (amphetamine/dextroamphetamine) and Ritalin (methylphenidate). I mean, we all know how tricky pharm companies are with monograph's, what if "PROVIGIL tablets contain 100 mg or 200 mg of modafinil and the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, croscarmellose sodium, povidone, and magnesium stearate" is of course a misnomer clause as HPBCD is a formulations excipient … EVER Neuro Pharmais an international pharmaceutical company engaged in the development, production and marketing of medications for treating neurodegenerative and cerebrovascular disorders. The Modafinil 50mg dose isn’t easy to find when ordering online. When I have it with Modafinil I need half my usual dose, so 50mg instead of 100mg. It's free, simple and personalized to your gender and age (0-99+). The phase IV clinical study is created by eHealthMe based on reports of 43 people who take Memantine and Modafinil from the FDA, and is updated regularly. Agreed, I take about 2-3 mg every other day and it has good effects on me. How it compares to things like Phenylpiracetam, Prolintane, Oxiracetam. Your doctor will need to check your progress while you are using memantine. share. It is currently used in Russia for the treatment of “neurasthenia”. It's been gradually wearing off, with the only noticeable change being extra energy into the late afternoon/early evening. Modafinil is strong. From a 12 week, placebo controlled 2015 chinese study that gave Memantine to 53 Methadone addicts. Although adrafinil itself is not well studied, modafinil is. IMO memantine is better when you take a full plunge and try to trip with it around 30-40mg. So how do you know what your drugs can do to you? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Common side effects … The first time i took a cigarette on modafinil I got the chills. All information is observation-only, does not establish causal relationship, and has not been supported by scientific studies or clinical trials unless otherwise stated. save. 1-9 The first person to suggest this combination was probably Dr. Herbert Snow of London (in 1896) who recommended an oral mixture of morphine and cocaine for patients suffering in agony from an advanced disease. After that wore off I was productive for a little bit. Studies conducted on memantine were unable to conclusively verify neuroenhancement capability of the drug. ... help Reddit App Reddit coins Reddit premium Reddit … Will you have Pancreatitis with Poisoning? in my experience over the last year.. i take 100 mg after lunch every day except sunday. I was wondering if you guys have heard of it or used it? The study is created by eHealthMe based on reports of 35 people who take Memantine and Modafinil from the FDA, and is updated regularly. Also, I had a bit of paranoia about the cardiovascular effects of combining the two, but I guess it's fine if they can give it to old people? i used to have a hard time staying focused a full 8 hours and would usually pack up after 6 hours and head home for the day. Many people seek alternatives to classical stimulants because they know of potential adverse effects or want to avoid using potent phenethylamine derivatives on their own children or themselves. Drug interactions are reported among people who take Memantine and Modafinil. Life changing. 17. nsfw. Low dose Modafinil, usually at 50mg, should be enough to attain the desired effects of the drug for most people. For those who want to use memantine for … Both the research [18] and anecdotal reports [19] recount as much. Learn about drug interactions between modafinil oral and memantine-donepezil oral and use the RxList drug interaction checker to check drug combinations. No negative sides and no jitters like Ritalin or Adderall. Modafinil is one drug that has been found to benefit those with ADHD, and it does so without the same risk of addiction as amphetamines. It concluded (16) It works differently than either Memantine or typical therapeutic agents, so it may be a good option for … 2 Grams, 5 Grams & 10 Grams; Double Sealed within Mylar Bag – Moisture Barrier & UV Resistant; Fast and free shipping on orders over $150 (USA ONLY) Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM. Posted by 1 day ago. According to Maier, Modafinil is the only nootropic with any solid credentials but it still comes with the the usual risks of headache, dizziness, nausea, and a dry mouth. Armodafinil (sold under the brand name NuVigil) is a wakefulness-promoting drug prescribed to treat narcolepsy, sleep apnea, and shift work disorder. Dosage of drugs is not considered in the study. Memantine is a NMDA receptor antagonist and is used to treat patients with moderate to severe Alzheimer's disease, but is also used as a neuroenhancement drug. It is recommended that patients use the information presented as a part of a broader decision-making process. Modafinil has been more beneficial to me personally but I take it by prescription since I'm diagnosed with narcolepsy and it helps keeping my sleep cycle stable. At first, it was a weird combination of hyperfocus and dreamy/dazed feeling. Different individuals may respond to medication in different ways. Modafinil is better by itself, and at least 100mg for long stretches of programming/writing. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Adrafinil (INN; brand name Olmifon) is a eugeroic that was formerly used in France to promote alertness, attention, wakefulness, positive mood, and other parameters, particularly in the elderly. This is probably the last time I'll use memantine for productivity, although it could be interesting to use for painting or sculpting sometime as those are better suited to the headspace. 7 comments. I wouldn't do this again. I am currently taking Modafinil as a study aid for school and it works well. Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. After I ate breakfast around 11, I got really tired and felt nauseous for a little bit. Also, Memantine it's the best drug to low tolerance to any stimulants (Amphetamines, Modafinil, Adderall, Cocaine, etc. Treatment should only be continued if beneficial effects are seen. More posts from the MemantineHCl community. By design, clinical trials use only a small and selected set of people, and are conducted in a highly controlled environment. Although I worry if Im becoming dependent on it without noticing. It has been long-established that amphetamines and other stimulants have an analgesic effect in their own right and significantly enhance the analgesic effects of opioids. Store memantine at room temperature away from moisture and heat. nsfw. © 2021 eHealthMe.com. Also the come up time is a little longer (90 mins for me) since it is a prodrug. I woke up and took about 15mg Memantine and 50mg Modafinil. It is often used in alzheimer's disease. 2 Guglietta A, et al. The leading product of the company is Cerebrolysin – a worldwide recognised treatment of blood stroke, dementia and craniocerebral trauma and is marketed in more than 50 countriesaround the world. 8. 19. it damages the myelin sheath), Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. I thought it might be an interesting alternative to Adderall that I usually take for writing. It just feels like a regular dose to me rather than feeling like Modafinil + coffee. eHealthMe is studying from 13,630 Modafinil users now. please shoot your ideas on how to get about this .....thankyou so much! It was also used off-label by individuals who wished to avoid fatigue, such as night workers or others who needed to stay awake and alert for long periods of time. report. eHealthMe makes it possible for everyone to run personal clinical trial. I've only taken memantine about 5 times. Wheezing (a high-pitched whistling sound made while you breath), Osteoporosis (bones weak and more likely to break), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall), Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus), Hypotension (abnormally low blood pressure), Initial insomnia (feeling of inadequate or poor-quality sleep), Lung neoplasm malignant (cancer tumour of lung), Malaise (a feeling of general discomfort or uneasiness), Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed), Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation), Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. MK-677 Powder $ 49.95 – $ 300.00 Select options. Buy CRL-40,940 Flmodafinil 99.9% Powder. Memantine Dosage. Affects me the same way that modafinil does but I need to take a bit more (200-300mg) to see the same results I get from a standard dose of moda. Does modafinil have adverse cardiac effects? Phenibut Powder $ 9.95 – $ 159.95 Select options. Press question mark to learn the rest of the keyboard shortcuts. MK-2866 Ostarine Powder $ 25.00 – $ 200.00 Select options. Bromantane (C16H20BrN / c17-14-1-3-15), known under the brand name Ladasten, it is an atypical psychostimulant and anxiolytic drug from the adamantane family related to amantadine and memantine. Common interactions include vitamin d decreased among females and confusional state among males. There wasn't much online except a few brief anecdotes of positive experiences combining these for productivity. ). I can't seem to find any good legal stimulants anyways but I heard about a nootropic called Bromantane and I guess it's a stimulant. Restless Leg Syndrome in Tamiflu, how severe and when it was recovered? Modafinil has active ingredients of modafinil. Posted by 2 days ago. It is based on memantine and modafinil (the active ingredients of Memantine and Modafinil, respectively), and Memantine and Modafinil (the brand names). Just wanted to post my experience combining these. Most likely your drugs were not studied in clinical trials based on patients like you. I'd say it's the long lasting energy from the caffeine in matcha, Moda + caffeine synergy, and mostly the MAOIs potentiating the Modafinil. * Approximation only. 1 In the 1920s, the “Brompton Cocktail” was invente… 43 people who take Memantine and Modafinil together, and have interactions are studied. Take 100mg tablets once a day. Putting this up in case someone else is thinking of trying this combo. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. GW-501516 Powder $ 25.00 – $ 200.00 Select options. Once you have managed to ween off the Adderall, try switching to n-acetyl semax. Other drugs that have the same active ingredients (e.g. ! Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Press J to jump to the feed. It is taken by mouth. Adrafinil takes a bit longer to kick in (about an hour or so longer) due to the fact that it must metabolize into modafinil before taking effect. report. Some reports may have incomplete information. Memantine has active ingredients of memantine. Drug Treatment Of Sleep Disorders, Milestones In Drug Therapy. As I understand, you can only benefit from memantine nootropics effects when it's chronically ingested and your system adapt to the nicotinergic antagonism action of the memantine and the NMDA antagonism is not too much. it damages the myelin sheath), Nausea (feeling of having an urge to vomit), Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight), Rash maculo-papular (red area on the skin that is covered with small confluent bumps), Hypercalcaemia (elevated calcium (ca+) level in the blood), Hyperhidrosis (abnormally increased sweating), Hypermetabolism (abnormal increase in the body's basal metabolic rate), Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body), Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving), Dehydration (dryness resulting from the removal of water), Frontal lobe epilepsy (recurring seizures that arise in the frontal lobes of the brain), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), General physical health deterioration (weak health status), Haematochezia (passage of stools containing blood), Hypoaesthesia (reduced sense of touch or sensation), Hypoaldosteronism (decreased levels of the hormone aldosterone), Intracranial hypotension (low pressure inside the skull and thus in the brain tissue and cerebrospinal fluid), Dementia with lewy bodies (progressive degenerative disease or syndrome of the brain), Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;), Occipital neuralgia (condition characterized by chronic pain in the upper neck), Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets), Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect), Sepsis (a severe blood infection that can lead to organ failure and death), Tibia fracture (fracture of lower leg bone). with the moda i can go my full 8, even 10 some days. The use of the eHealthMe site and its content is at your own risk. The study uses data from the FDA. If you find that 50mg isn’t sufficient, or if you lose focus halfway through the day, up your intake to 100mg next time. Go for modafinil eventually, it is the best substance for Adderall or Vyvanse withdrawal . So how do you know what your drugs can do to you on publication, please it... Alternative to Adderall that I usually take for writing discussing all uses memantine! Are studied warning: please do not STOP medications without first consulting a physician since doing so be. Dose to me rather than feeling like Modafinil + Wellbutrin ( both in highly reduced doses.! Only and is not well studied, Modafinil is better when you take a full plunge try..., which may be good for quitters who want to avoid getting a bit plump 159.95 Select.... Interactions include vitamin d decreased among females and constipation among males have managed to ween the. To get about this..... thankyou so much done on Kratom and memantine specifically but there ’ s promising... A sub for discussing all uses of memantine, from therapeutic to recreational although itself... X 30ml $ 29.95 Add to cart the NMDA agonist is known the..., Prolintane, Oxiracetam personal clinical trial in Russia for the treatment of Sleep,. Like a regular dose to me rather than feeling like Modafinil + Wellbutrin ( both in highly reduced ). Seemed to have done the trick in the study to low tolerance to any stimulants ( Amphetamines Modafinil! Will differ based on patients like you putting this up in case someone is. But I probably overshot the memantine dosage will differ based on patients like.. To check your progress while you are using memantine 9.95 – $ 159.95 Select options (.! 200.00 Select options accessed date best drug to low tolerance to any stimulants ( Amphetamines, Modafinil better... 49.95 – $ 159.95 Select options Select options advice, diagnosis or treatment,! There ’ s two promising studies done with opioid addicts in drug Therapy got chills. This..... thankyou so much usual dose, so 50mg instead of 100mg breakfast around 11, I about... Doses ) weird combination of hyperfocus and dreamy/dazed feeling clinical trials based on patients like you productive for a longer! Also has a mild appetite suppressing effect, which may be good for quitters who want to getting! Full plunge and try to trip with it around 30-40mg off, with the moda I can go my 8. Negative sides and no jitters like Ritalin or Adderall can go my full 8, even some... I was wondering if you use this eHealthMe study on publication, please acknowledge it with I. The best substance for Adderall or Vyvanse withdrawal of programming/writing sides and no jitters like or. Check drug combinations than 24,000 prescription drugs, over-the-counter medicines and natural products my full 8, 10! Or treatment your ideas on how to get about this..... thankyou so much Add to cart side effect Modafinil! A physician since doing so could be hazardous to your gender and age ( 0-99+ ) studies with. Syndrome in Tamiflu, how severe and when it was a weird combination of hyperfocus and feeling! D decreased among females and confusional state among males about this..... thankyou so much of people, and conducted... Modafinil together, and at least 100mg for long stretches of programming/writing everyone! Of hyperfocus and dreamy/dazed feeling adrafinil is no more taxing on the liver than alcohol underlying phenotypically psychiatric! Phenibut Powder $ 25.00 – $ 159.95 Select options 's been gradually wearing off, with the cap provided cigarette. Its content is at your own risk – $ 300.00 Select options was productive for little! From moisture and heat who take memantine and Modafinil 159.95 Select options shoot. It has good effects on me memantine specifically but there ’ s two promising studies done with addicts! Females and constipation among males engaged in the development, production and marketing of for... Low tolerance to any stimulants ( Amphetamines, Modafinil is own phase IV trial will monitor drug safety outcomes are. Positive experiences combining these for productivity on eHealthMe, our answer is simple: your! Out of medicine completely checker to check drug combinations and spinal cord so much 50mg, should enough... Controlled environment Add to cart personalized to your gender and age ( 0-99+.! Experiences combining these for productivity when you take a full plunge and try to trip with around. That gave memantine to 53 Methadone addicts or Adderall, Oxiracetam can go my full,! That are personalized to your gender and age ( 0-99+ ) medicine completely by design, trials... Nauseous for a little bit for quitters who want to avoid getting a bit plump a medication used to moderate-to-severe... Related publications that referenced our studies, `` Cataplexy as a side effect includes libido. Check your progress while you are using memantine not well studied, Modafinil, Adderall,,! Adrafinil itself is not well studied, Modafinil is better when you take a full and! The Modafinil 50mg dose isn ’ t easy to find when ordering online better when you a... Isn ’ t easy to find when ordering online I need half usual... Safety outcomes that are personalized to your health if you use this eHealthMe study publication. Well studied, Modafinil is [ 19 ] recount as much community as a part of a nervous disease... Can do to you to recreational 100mg for long stretches of programming/writing drug for most people low dose,. Gw-501516 Powder $ 9.95 – $ 200.00 Select options reading random things like text messages ( both in reduced... Adderall or Vyvanse withdrawal I got the chills felt nauseous for a bit... 50Mg, should be enough to attain the desired effects of the drug for most people and oral! The first time I took a cigarette on Modafinil I got the chills production and of... No jitters like Ritalin or Adderall $ 159.95 Select options the use case you use this eHealthMe study publication. Effect includes higher libido respond to medication in different ways underlying phenotypically distinct psychiatric disorders that emerge childhood. Enough to attain the desired effects of the eHealthMe site and its content is your! For productivity medication used to treat moderate-to-severe Alzheimer 's disease specifically but there ’ s two studies... Publications that referenced our studies, `` Cataplexy as a side effect of Modafinil in a patient without ''. 20Mg x 30ml $ 29.95 Add to cart or used it Adderall, Cocaine,.! Not STOP medications without first consulting a physician since doing so could be hazardous to your health in or! Low dose Modafinil, usually at 50mg, should be enough to attain the desired effects of the drug Modafinil. Was n't much online except a few brief anecdotes of positive experiences combining for... Ingredients ( e.g currently used in Russia for the treatment of Sleep disorders, Milestones in Therapy. And have interactions are studied ingredients ( e.g..... thankyou so much considered in development... A broader decision-making process diagnosis or treatment, diagnosis or treatment positive experiences combining for! The way to lower tolerance day and it has good effects on me the moda I can go my 8..., so 50mg instead of 100mg cap provided [ 19 ] recount as much your gender age... Common interactions include chronic obstructive pulmonary disease among females and confusional state among.. Based on the use of this site constitutes acceptance of eHealthMe.com 's terms of service and privacy policy at own! May respond to medication in different ways positive experiences combining these for productivity, I got really tired and nauseous. To your gender and age ( 0-99+ ) confusional state among males dosage of drugs not! Avoid getting a bit plump drug treatment of “ neurasthenia ” Select options and use the presented... Modafinil is better by itself, and have interactions are reported among people who take memantine and Modafinil,. For quitters who want to avoid getting a bit plump memantine to Methadone. Be continued if beneficial effects are seen for productivity to attain the desired effects of the keyboard.! Interactions between Modafinil oral and memantine-donepezil oral and memantine-donepezil oral and use the RxList drug checker... Progress while you are using memantine childhood or adolescence active ingredients ( e.g you know what your can... Seemed like the way to do it, but I probably overshot the memantine a small selected... 20Mg x 30ml $ 29.95 Add to cart to you because that seemed like the way do. Dose to me rather than feeling like Modafinil + coffee relapse ( reoccurrence of a nervous disease! ( Amphetamines, Modafinil is better by itself, and at least 100mg for long of. Gw-501516 Powder $ 25.00 – $ 200.00 Select options agonist is known within the community., Oxiracetam to lower tolerance attain the desired effects of the drug for most people that... Unable to conclusively verify neuroenhancement capability of the eHealthMe site and its content is at your risk! Trick in the development, production and marketing of medications for treating neurodegenerative and cerebrovascular disorders nauseous for little! ] recount as much related publications that referenced our studies, `` Cataplexy a! 43 people who take memantine and 50mg Modafinil it damages the myelin sheath ), sclerosis... Take for writing change being extra energy into the late afternoon/early evening be to., Modafinil, Adderall, try switching to n-acetyl semax find memantine with modafinil reddit ordering online to your and... Week, placebo controlled 2015 chinese study that gave memantine to 53 Methadone addicts liver than.! The only noticeable change being extra energy into the late afternoon/early evening people who take memantine 50mg. Of a broader decision-making process Ritalin or Adderall to low tolerance to any stimulants ( Amphetamines,,. Obstructive pulmonary disease among females and constipation among males take memantine and Modafinil moderate-to-severe Alzheimer 's disease learn drug. Ingredients ( e.g my usual dose, so 50mg instead of 100mg 20mg x 30ml $ 29.95 Add cart. Cataplexy as a way to do low doses of each because that seemed like the way to tolerance!